Juvederm Dermal Fillers
The world's leading family of hyaluronic acid dermal fillers by Allergan Aesthetics, an AbbVie company. Six specialized formulas for natural-looking facial rejuvenation.
What Is Juvederm?
Juvederm is a collection of FDA-approved hyaluronic acid dermal fillers manufactured by Allergan Aesthetics (AbbVie) and is the most popular filler brand in the United States. The product line includes six specialized formulas -- Ultra XC, Voluma XC, Vollure XC, Volbella XC, Volux XC, and Ultra Plus XC -- each engineered using VYCROSS technology for specific treatment areas including lips, cheeks, jawline, and wrinkles. Results last 12 months to 2 years depending on the product used.
What Is Juvederm?
Juvederm is a collection of FDA-approved hyaluronic acid (HA) dermal fillers manufactured by Allergan Aesthetics, part of AbbVie. As the most popular dermal filler brand in the United States, Juvederm has been trusted by millions of patients and providers since its initial FDA approval in 2006. The product line has expanded over the years to include six specialized formulas, each engineered to address specific treatment areas and aesthetic goals.
Hyaluronic acid is a naturally occurring sugar molecule found in your skin, connective tissues, and joints. It plays a critical role in maintaining hydration and volume -- a single molecule of HA can hold up to 1,000 times its weight in water. As we age, our natural HA levels decline, contributing to wrinkles, folds, and volume loss. Juvederm fillers replace this lost HA to restore a smoother, more youthful appearance.
VYCROSS and Hylacross Technology
What sets Juvederm apart from other HA fillers is its proprietary cross-linking technology. Allergan uses two distinct manufacturing processes to create fillers with different properties suited to different treatment areas:
VYCROSS Technology
Used in Voluma XC, Vollure XC, Volbella XC, and Volux XC. VYCROSS blends high and low molecular weight HA chains with a highly efficient cross-linking process, resulting in a smooth, cohesive gel that lifts and supports tissue while maintaining a natural feel. VYCROSS products tend to last longer and require less product per treatment.
Hylacross Technology
Used in Juvederm Ultra XC and Ultra Plus XC. Hylacross creates a highly cross-linked, smooth gel with excellent flow properties, making it ideal for soft tissue areas like the lips and perioral lines. These formulations integrate smoothly into tissue for natural-feeling results.
The Complete Juvederm Product Line
Juvederm Ultra XC
HylacrossThe go-to choice for lip augmentation and smoothing moderate perioral lines (smoker's lines). Ultra XC provides fuller, plumper lips with natural movement and a soft feel. Contains lidocaine for added comfort during treatment.
Duration: Up to 12 months | Treatment areas: Lips, perioral lines
Juvederm Ultra Plus XC
HylacrossA more robust formulation designed for deeper injection to correct moderate to severe nasolabial folds (smile lines) and facial wrinkles. Ultra Plus XC has a higher concentration of cross-linked HA for greater lifting capacity.
Duration: Up to 12 months | Treatment areas: Nasolabial folds, deeper wrinkles
Juvederm Voluma XC
VYCROSSThe first FDA-approved filler for cheek augmentation and midface volume restoration. Voluma XC provides a subtle lift that counters age-related volume loss in the cheek area, restoring youthful facial contours. It is also used for chin augmentation.
Duration: Up to 2 years | Treatment areas: Cheeks, midface, chin
Juvederm Vollure XC
VYCROSSDesigned specifically for moderate to severe facial wrinkles and folds, particularly nasolabial folds. Vollure XC uses VYCROSS technology to create a soft, flexible gel that moves naturally with your facial expressions while providing lasting correction.
Duration: Up to 18 months | Treatment areas: Nasolabial folds, marionette lines
Juvederm Volbella XC
VYCROSSA delicate formulation for subtle lip augmentation and correction of perioral lines. Volbella XC uses a lower concentration of HA for soft, natural results -- ideal for patients who want lip enhancement without an overdone look. Also used for under-eye hollows (tear troughs).
Duration: Up to 12 months | Treatment areas: Lips (subtle), perioral lines, under-eyes
Juvederm Volux XC
VYCROSSThe newest addition to the Juvederm family and the first FDA-approved HA filler specifically for jawline definition. Volux XC is the firmest VYCROSS product, providing strong structural support to create a more defined, sculpted jawline.
Duration: Up to 18-24 months | Treatment areas: Jawline, chin
Key Facts at a Glance
Hyaluronic Acid
Duration Range
Product Formulas
Reversible
What to Expect During Treatment
A Juvederm treatment session typically takes 15 to 60 minutes depending on the number of areas being treated. Here is what the process generally involves:
Consultation
Your provider will evaluate your facial anatomy, discuss your goals, review your medical history, and recommend the appropriate Juvederm product or combination of products.
Preparation
The treatment area is cleaned and a topical numbing cream may be applied for 15-20 minutes. Your provider will mark injection points on your skin.
Injection
Using a fine needle or blunt-tipped cannula, your provider injects Juvederm into the targeted areas. The built-in lidocaine numbs the area as the product is placed. Most patients feel only mild pressure or a brief pinch.
Aftercare
You will see results immediately. Mild swelling, redness, or bruising may occur and typically resolves within a few days. You can return to most normal activities right away, though strenuous exercise should be avoided for 24-48 hours.
Cost Ranges
Juvederm is priced per syringe, and the total cost depends on which product is used and how many syringes are needed to achieve your desired results. Here are general cost ranges:
| Product | Cost Per Syringe | Typical Syringes |
|---|---|---|
| Ultra XC | $600 - $800 | 1-2 (lips) |
| Ultra Plus XC | $650 - $900 | 1-2 (folds) |
| Voluma XC | $800 - $1,200 | 1-2 per side (cheeks) |
| Vollure XC | $650 - $900 | 1-2 (folds) |
| Volbella XC | $500 - $800 | 1 (lips/lines) |
| Volux XC | $900 - $1,200 | 2-4 (jawline) |
Prices vary by geographic location and provider. Allergan offers the Alle rewards program, which provides savings on future treatments.
Juvederm vs. Restylane
Juvederm and Restylane are both hyaluronic acid fillers and are the two most widely used HA filler brands in the world. While they serve similar purposes, there are notable differences:
| Feature | Juvederm | Restylane |
|---|---|---|
| Manufacturer | Allergan Aesthetics (AbbVie) | Galderma |
| Technology | VYCROSS / Hylacross | NASHA / OBT / XpresHAn |
| Texture | Smoother, more cohesive | Firmer, more granular |
| Product Count | 6 formulas | 9 formulas |
| Unique Strength | Jawline definition (Volux) | Under-eye (Eyelight) |
Both product families produce excellent results. The choice often comes down to your provider's experience and preference, the specific treatment area, and your individual anatomy. Many providers use both brands interchangeably.
Frequently Asked Questions About Juvederm
How long does Juvederm last?
Juvederm results vary by product. Juvederm Ultra XC and Volbella XC last up to 12 months, Vollure XC lasts up to 18 months, and Voluma XC can last up to 2 years. Individual results depend on the treatment area, amount of product used, and your metabolism. Touch-up treatments can help maintain results over time.
What is the difference between Juvederm and Restylane?
Both are hyaluronic acid fillers, but they use different cross-linking technologies. Juvederm uses VYCROSS and Hylacross technology for smooth, cohesive gels, while Restylane uses NASHA and OBT technology. Juvederm tends to have a smoother consistency, while some Restylane products offer more structural support. Your provider can recommend which is best for your goals.
Does Juvederm hurt?
Most patients experience only mild discomfort. All Juvederm XC products contain lidocaine, a built-in numbing agent that significantly reduces pain during injection. Many providers also apply topical numbing cream before treatment. Most patients describe the sensation as a brief pinch or pressure that is very manageable.
Can Juvederm be dissolved if I don't like the results?
Yes. Because Juvederm is made of hyaluronic acid, it can be dissolved using an enzyme called hyaluronidase (Hylenex). This is one of the key safety advantages of HA fillers. If you are unhappy with your results or experience a complication, your provider can inject hyaluronidase to break down the filler, typically within 24-48 hours.
How much does Juvederm cost?
Juvederm costs typically range from $600 to $1,200 per syringe, depending on the specific product and geographic location. Most lip treatments require 1-2 syringes, cheek augmentation typically uses 1-2 syringes per side, and jawline contouring may require 2-4 syringes. Your provider will give you an exact cost estimate during your consultation. Allergan's Alle rewards program can help offset costs on future treatments.
Who should not get Juvederm?
Juvederm is not recommended for patients with severe allergies, a history of anaphylaxis, allergies to lidocaine or gram-positive bacterial proteins, or those who are pregnant or breastfeeding. Patients with bleeding disorders or those taking blood-thinning medications should discuss risks with their provider before treatment. Always disclose your full medical history during your consultation.
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